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Biostatistics and Epidemiology

A Primer for Health and Biomedical Professionals

  • Textbook
  • © 2015

Overview

  • Updated edition of a classic text that has brought biostatistics and epidemiology to a broad audience in a very accessible way
  • Easily understandable by readers with a non-mathematical background
  • Covers the design, analysis and interpretation of observational studies, randomized trials and even genetic research
  • Includes topics not usually found in introductory text books, such as propensity analysis, quality of life measures, genome wide association studies, evaluation of new biomarkers

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Table of contents (10 chapters)

Keywords

About this book

Since the publication of the first edition, Biostatistics and Epidemiology has attracted loyal readers from across specialty areas in the biomedical community. Not only does this textbook teach foundations of epidemiological design and statistical methods, but it also includes topics applicable to new areas of research. Areas covered in the fourth edition include a new chapter on risk prediction, risk reclassification and evaluation of biomarkers, new material on propensity analyses, and a vastly expanded chapter on genetic epidemiology, which  is particularly relevant to those who wish to understand the epidemiological and statistical aspects of scientific articles in this rapidly advancing field. Biostatistics and Epidemiology was written to be accessible for readers without backgrounds in mathematics. It provides clear explanations of underlying principles, as well as practical guidelines of "how to do it" and "how to interpret it." Key features include a philosophical and logical explanation at the beginning of the book, subsections that can stand alone or serve as reference, cross-referencing, recommended reading, and appendices covering sample calculations for various statistics in the text. 

Reviews

“The intended audience includes physicians doing clinical or basic research; medical students and college or graduate level students; researchers in biomedical sciences and epidemiology as well as those interested in genetic epidemiology; and anyone interested in the logic and methodology of biostatistics, epidemiology, and genetic epidemiology. … This book presents the basics on biostatistics and epidemiology in biomedical science and incorporates new information on genetic epidemiology and risk prediction based on new biomarkers.” (Hemang B. Panchal, Doody's Book Reviews, June, 2015)

Authors and Affiliations

  • Department of Epidemiology, Albert Einstein College of Medicine, Bronx, USA

    Sylvia Wassertheil-Smoller

  • Department of Psychiatry and Center for Human Genetic Research, Massachusetts General Hospital, Boston, USA

    Jordan Smoller

About the authors

Sylvia Wassertheil-Smoller, Ph.D. is Professor of epidemiology in the Department of Epidemiology and Population Health at the Albert Einstein College of Medicine and is the Dorothy and William Manealoff Foundation and Molly Rosen Chair in Social Medicine, Emerita. In addition to her teaching, her research areas span both cardiovascular disease and cancer epidemiology. She has been a leader in landmark clinical trials in the prevention of heart disease and stroke and in major national and international collaborative prospective studies. She has won awards for mentoring students and junior faculty, as well as the Einstein Sprit of Achievement Award. She lives in New York.

Jordan Smoller, MD, ScD, is Professor of Psychiatry at Harvard Medical School and Professor in the Department of Epidemiology at the Harvard School of Public Health in Boston. He is Director of the Psychiatric and Neurodevelopmental Genetics Unit in the Massachusetts General Hospital (MGH)Center for Human Genetics Research. He is  also an Associate Member of the Broad Institute and a Senior Scientist at the Broad's Stanley Center for Psychiatric Research. The focus of Dr. Smoller's research  has been the identification of genetic determinants of childhood and adult psychiatric disorders and of genetic factors common to multiple psychiatric conditions. He is the recipient of numerous research awards, an author of more than 200 scientific articles, book chapters and reviews; as well as the author of the book: The Other Side of Normal (HarperCollins/William Morrow, 2012). He lives with his family in Boston.

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