Sequence Comparison

Theory and Methods

By Kun-Mao Chao , Louxin Zhang

Sequence Comparison Cover Image

Biomolecular sequence comparison is the origin of bioinformatics. This book gives a complete in-depth treatment of the study of sequence comparison. The book examines alignment methods and techniques, and features a new issue of sequence comparison.

Full Description

  • ISBN13: 978-1-8480-0319-4
  • 232 Pages
  • User Level: Science
  • Publication Date: November 27, 2008
  • Available eBook Formats: PDF
  • eBook Price: $119.00
Buy eBook Buy Print Book Add to Wishlist

Related Titles

Full Description
Biomolecular sequence comparison is the origin of bioinformatics. This book gives a complete in-depth treatment of the study of sequence comparison. A comprehensive introduction is followed by a focus on alignment algorithms and techniques, proceeded by a discussion of the theory. The book examines alignment methods and techniques, features a new issue of sequence comparison - the spaced seed technique, addresses several new flexible strategies for coping with various scoring schemes, and covers the theory on the significance of high-scoring segment pairs between two unalignment sequences. Useful appendices on basic concepts in molecular biology, primer in statistics and software for sequence alignment are included in this reader-friendly text, as well as chapter-ending exercise and research questions A state-of-the-art study of sequence alignment and homology search, this is an ideal reference for advanced students studying bioinformatics and will appeal to biologists who wish to know how to use homology search tools.
Table of Contents

Table of Contents

  1. Introduction.
  2. Part I: Algorithms and Techniques.
  3. Basic Algorithmic Techniques.
  4. Pairwise Sequence Alignment.
  5. Homology Search Tools.
  6. Multiple Sequence Alignment.
  7. Part II: Theory.
  8. Anatomy of Spaced Seeds.
  9. Local Alignment Statistics.
  10. Scoring Matrices.
  11. A: Basic Concepts in Molecular Biology.
  12. B: Elementary Probability Theory.
  13. C: Software Packages for Sequence Alignment.
  14. Index.
Errata

Please Login to submit errata.

No errata are currently published