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Computational Biology

Protein-protein Interactions and Networks

Identification, Computer Analysis, and Prediction

Editors: Panchenko, Anna, Przytycka, Teresa M. (Eds.)

  • Integrates different approaches which contribute to the understanding of the most recent advances in the field of protein-protein interactions and protein interaction networks
  • Includes a review of experimental techniques, databases and various computational methods for prediction and analysis of protein interactions and their networks
  • Provides comprehensive coverage
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eBook $139.00
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  • ISBN 978-1-84800-125-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
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  • Download immediately after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-84800-124-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • ISBN 978-1-84996-731-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The biological interactions of living organisms, and protein-protein interactions in particular, are astonishingly diverse and present numerous challenges to modern biomolecular research because of their complexity. Analysis of patterns and principles governing these interactions has prompted a rapid development of computational methods to identify protein interaction partners and to understand the roles of individual components of protein interaction networks in cell functions.

This book integrates different approaches from bioinformatics, biochemistry, computational analysis and systems biology to offer the reader a comprehensive global view of the diverse data on protein-protein interactions and protein interaction networks. It brings together the descriptions of experimental techniques and expounds on different computational algorithms for protein network analysis and prediction of protein and domain interactions, with each chapter containing a description of the problem, a review of methods and algorithms, a list of resources and current conclusions.

Features

• Reviews experimental techniques for identification of protein interactions

• Discusses protein interaction databases and methods of integrating data from diverse sources

• Describes computational methods to predict protein and domain interaction partners

• Explores the properties of interaction interfaces and highlights approaches to model the assembly of protein complexes

• Examines the topological and dynamical properties of protein interaction networks and presents the tools for comparative analysis of these networks

Written by leading experts, Protein-protein Interactions and Networks provides a broad, thorough and multidisciplinary coverage of this field. It will be invaluable to researchers from academia and the bioinformatics industry, as well as an excellent auxiliary text for graduate students studying the topic.

Reviews

From the reviews:

"This book consists of nine papers, written by diverse authors, each of which discusses specific problems in the area of protein-protein interactions, and different approaches to solving these problems. … offers a high-level overview of computational methods for predicting protein interactions. … This book is geared more toward biologist … ." (D. Bollman, ACM Computing Reviews, January, 2009)


Table of contents (9 chapters)

  • Experimental Methods for Protein Interaction Identification and Characterization

    Uetz, Peter (et al.)

    Pages 1-32

  • Handling Diverse Protein Interaction Data: Integration, Storage and Retrieval

    Shoemaker, Benjamin (et al.)

    Pages 33-51

  • Principles of Protein Recognition and Properties of Protein-protein Interfaces

    Keskin, Ozlem (et al.)

    Pages 53-65

  • Computational Methods to Predict Protein Interaction Partners

    Valencia, Alfonso (et al.)

    Pages 67-81

  • Protein Interaction Network Based Prediction of Domain-Domain and Domain-Peptide Interactions

    Guimarães, Katia S. (et al.)

    Pages 83-98

Buy this book

eBook $139.00
price for USA
  • ISBN 978-1-84800-125-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Download immediately after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-84800-124-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • ISBN 978-1-84996-731-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.

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Bibliographic Information

Bibliographic Information
Book Title
Protein-protein Interactions and Networks
Book Subtitle
Identification, Computer Analysis, and Prediction
Editors
  • Anna Panchenko
  • Teresa M. Przytycka
Series Title
Computational Biology
Series Volume
9
Copyright
2008
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London
eBook ISBN
978-1-84800-125-1
DOI
10.1007/978-1-84800-125-1
Hardcover ISBN
978-1-84800-124-4
Softcover ISBN
978-1-84996-731-0
Series ISSN
1568-2684
Edition Number
1
Number of Pages
VIII, 212
Number of Illustrations and Tables
39 b/w illustrations
Topics