Overview
- Lipidomic analysis of key metabolic processes
- Novel lipid- based therapeutic proposal for neurodegenerative diseases
- 12 chapters and almost 50 color figures and tables
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1127)
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Table of contents (12 chapters)
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Front Matter
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Structure, Characterization and Physicochemical Properties of Bioactive Lipids
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Front Matter
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Signaling Cascades Mediated by Bioactive Lipids
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Front Matter
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Bioactive Lipids in Inflammatory and Cardiovascular Diseases
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Front Matter
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Role of Bioactive Lipids in Neurodegenerative Diseases
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Front Matter
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Back Matter
Keywords
About this book
The purpose of this book is to introduce the readers on the perspective of the role that unsaturated fatty acids and complex lipids play on health and disease. Bioactive lipids can be modified affecting membrane composition, structure and fluidity in addition to changes in cell signaling associated to lipid-protein (membrane receptors) interactions, issues that are addressed by the authors. This book analyzes key topics involving bioactive lipids and their role in normal signaling and the mechanisms of disease. The book navigates from structural studies of oxidized and non-oxidized lipids to the reactions and cell signaling processes that bioactive lipids play in cardiovascular and neurodegenerative diseases. The book contains the recent advances reported in the literature about lipidomics as well as the role that lipid-derived compounds exert on unfolded protein response and lipid metabolism and disease. This book represents a state of the art introduction to lipid metabolism from a biochemical to an in vivo overview being an useful tool for students and investigators. We hope the mechanistic observations on the role of bioactive lipids in health and disease serve a perspective to improve the existing treatments or propose new lipid-based pharmacology
Editors and Affiliations
About the editors
Homero Rubbo is a professor in the department of Biochemistry at the University de la Republica in Montevideo, Uruguay.
Bibliographic Information
Book Title: Bioactive Lipids in Health and Disease
Editors: Andres Trostchansky, Homero Rubbo
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-030-11488-6
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2019
Hardcover ISBN: 978-3-030-11487-9Published: 12 June 2019
eBook ISBN: 978-3-030-11488-6Published: 28 May 2019
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VIII, 198
Number of Illustrations: 6 b/w illustrations, 35 illustrations in colour
Topics: Human Genetics, Human Physiology, Neurochemistry, Molecular Medicine, Protein Science, Cardiovascular Biology