Pain and Neuroimmune Interactions
Editors: Saadé, Nayef E., Jabbur, Suhayl J., Apkarian, A. Vania (Eds.)
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- About this book
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For those of us involved in research on the neural mechanisms that relate tissue damage to pain. it is becoming more evident that the sensation of pain and suffering could be considered as part of a mechanism that involves not only sizeable areas in the brain but also simultaneous activations of the immune and the endocrine systems as well. A consensus is growing among specialists in the field that pain involves the sharing of molecular mechanisms between the nervous, immune and endocrine systems that can interact at peripheral and, ultimately, central levels. Furthermore, chronic pain could then be looked upon as a corollary of the imbalance in the cross talk between these systems, which could lead to new treatment strategies. The aim of this book is not to deal with acute pain that serves as an alarm signal, but to attempt to explain the molecular mechanisms of chronic pains considered as a multifactorial syndrome or disease.
- Table of contents (18 chapters)
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Persistent Hyperalgesia and Cytokines
Pages 3-8
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Nociceptor Excitation by Sensitization: A Novel Hypothesis, Its Cellular and Molecular Background
Pages 9-19
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Tachykinins in Visceral Pain and Hyperalgesia
Pages 21-29
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Bradykinin, Cytokines and Inflammatory Hyperalgesia
Pages 31-54
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Neurotransmitter and Inflammatory Correlates in Experimental Neuropathy: Modulation by Electric Spinal Cord Stimulation
Pages 57-68
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Table of contents (18 chapters)
Bibliographic Information
- Bibliographic Information
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- Book Title
- Pain and Neuroimmune Interactions
- Editors
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- Nayef E. Saadé
- Suhayl J. Jabbur
- A. Vania Apkarian
- Copyright
- 2000
- Publisher
- Springer US
- Copyright Holder
- Springer Science+Business Media New York
- eBook ISBN
- 978-1-4615-4225-4
- DOI
- 10.1007/978-1-4615-4225-4
- Hardcover ISBN
- 978-0-306-46371-6
- Softcover ISBN
- 978-1-4613-6897-7
- Edition Number
- 1
- Number of Pages
- X, 244
- Topics
