Cell Surface Receptors: A Short Course on Theory and Methods

1. Front Matter

   Pages i-xvii

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2. Historical Perspective

   • Lee E. Limbird

   Pages 1-26

3. Methods for Characterization of Receptors Based on Receptor-Mediated Responses in Tissue or Intact Cell Preparations

   • Lee E. Limbird

   Pages 27-60

4. Identification of Receptors Using Direct Radioligand Binding Techniques

   • Lee E. Limbird

   Pages 61-122

5. Complex Binding Phenomena

   • Lee E. Limbird

   Pages 123-167

6. The Preparation and Study of Detergent-Solubilized Receptors

   • Lee E. Limbird

   Pages 169-199

7. The Topographical Fate of Ligand-Receptor Complexes as Reflected by the Properties of Ligand Binding to Intact Cells

   • Lee E. Limbird

   Pages 201-232

8. Back Matter

   Pages 233-238

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Cell Surface Receptors: A Short Course on Theory and Methods, Second Edition is a primer for the study of cell surface receptors. The simplified discussion of methods and their underlying principles removes the usual intimidation caused by the specialized vocabulary or sophisticated mathematics that characterize many of the primary papers in this field. In this way, the basic concepts become emphasized. This volume is a starting point: a textbook as well as a manual to which the investigator can return for a refresher course, when needed.

• cell
• cell surface receptors
• membrane
• pharmacology
• research
• tissue

• Vanderbilt University, Nashville, USA

  Lee E. Limbird

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