Neuromuscular Diseases

A Practical Approach to Diagnosis and Management

Authors: Swash, Michael, Schwartz, Martin S.

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  • theoretical information that will be useful to managing patients with neuromuscular problems. Both authors are recognised experts in the field of neuromuscular disorders and the book is based on their extensive and continuing clinical and research experience.

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  • ISBN 978-1-4471-3834-1
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About this book

Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders. As a result many previously unrecognised disorders have been charac­ terised. Some clinical syndromes, such as the limb girdle dystrophies, have become better defined. In many such instances the new genetic information has led to major advances in knowledge of the biology of cell structures, for example, the membrane structural and channel proteins. The clinical syndromes themselves, and their patho­ logical and electrophysiological characteristics, however, remain as important as ever, since they constitute the clinical problem itself and, indeed, the database from which all other concepts emerge. Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. However, this informa­ tion does not necessarily always define clinically useful syndromes. Myotonia, for example, is an electrophysiological finding in some syndromes in which it is un­ detectable by clinical examination, although the phenomenon itself was originally defined as a clinical entity. The limb girdle muscular dystrophy syndromes can be defined by severity, distribution of weakness, age of onset, sex distribution and other characteristics and many of these can be better understood by study of the under­ lying defect in cell structural proteins.

Table of contents (21 chapters)

Table of contents (21 chapters)
  • Clinical Assessment and Measurement

    Pages 1-17

    Swash, Michael, MD, FRCP, FRCPath (et al.)

  • Electromyography, Nerve Conduction and Other Neurophysiological Techniques

    Pages 19-42

    Swash, Michael, MD, FRCP, FRCPath (et al.)

  • Muscle and Nerve Biopsies

    Pages 43-68

    Swash, Michael, MD, FRCP, FRCPath (et al.)

  • Pathophysiological Correlations and Compensatory Mechanisms

    Pages 69-84

    Swash, Michael, MD, FRCP, FRCPath (et al.)

  • Classification of Neuromuscular Diseases

    Pages 85-87

    Swash, Michael, MD, FRCP, FRCPath (et al.)

Buy this book

eBook $84.99
price for USA
  • ISBN 978-1-4471-3834-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $109.00
price for USA

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Bibliographic Information

Bibliographic Information
Book Title
Neuromuscular Diseases
Book Subtitle
A Practical Approach to Diagnosis and Management
Authors
Copyright
1997
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London
Distribution Rights
Distribution rights for Taiwan: YEE LEE Book Co., Ltd.
eBook ISBN
978-1-4471-3834-1
DOI
10.1007/978-1-4471-3834-1
Softcover ISBN
978-1-4471-3836-5
Edition Number
3
Number of Pages
XVIII, 541
Number of Illustrations
331 b/w illustrations
Additional Information
Jointly published with YEE LEE Book Co., Ltd.
Topics