Neuromuscular Diseases
A Practical Approach to Diagnosis and Management
Authors: Swash, Michael, Schwartz, Martin S.
Free Preview- theoretical information that will be useful to managing patients with neuromuscular problems. Both authors are recognised experts in the field of neuromuscular disorders and the book is based on their extensive and continuing clinical and research experience.
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- About this book
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Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders. As a result many previously unrecognised disorders have been charac terised. Some clinical syndromes, such as the limb girdle dystrophies, have become better defined. In many such instances the new genetic information has led to major advances in knowledge of the biology of cell structures, for example, the membrane structural and channel proteins. The clinical syndromes themselves, and their patho logical and electrophysiological characteristics, however, remain as important as ever, since they constitute the clinical problem itself and, indeed, the database from which all other concepts emerge. Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. However, this informa tion does not necessarily always define clinically useful syndromes. Myotonia, for example, is an electrophysiological finding in some syndromes in which it is un detectable by clinical examination, although the phenomenon itself was originally defined as a clinical entity. The limb girdle muscular dystrophy syndromes can be defined by severity, distribution of weakness, age of onset, sex distribution and other characteristics and many of these can be better understood by study of the under lying defect in cell structural proteins.
- Table of contents (21 chapters)
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Clinical Assessment and Measurement
Pages 1-17
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Electromyography, Nerve Conduction and Other Neurophysiological Techniques
Pages 19-42
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Muscle and Nerve Biopsies
Pages 43-68
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Pathophysiological Correlations and Compensatory Mechanisms
Pages 69-84
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Classification of Neuromuscular Diseases
Pages 85-87
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Table of contents (21 chapters)
Bibliographic Information
- Bibliographic Information
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- Book Title
- Neuromuscular Diseases
- Book Subtitle
- A Practical Approach to Diagnosis and Management
- Authors
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- Michael Swash
- Martin S. Schwartz
- Copyright
- 1997
- Publisher
- Springer-Verlag London
- Copyright Holder
- Springer-Verlag London
- Distribution Rights
- Distribution rights for Taiwan: YEE LEE Book Co., Ltd.
- eBook ISBN
- 978-1-4471-3834-1
- DOI
- 10.1007/978-1-4471-3834-1
- Softcover ISBN
- 978-1-4471-3836-5
- Edition Number
- 3
- Number of Pages
- XVIII, 541
- Number of Illustrations
- 331 b/w illustrations
- Additional Information
- Jointly published with YEE LEE Book Co., Ltd.
- Topics
