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Steroid Contraceptives and Women’s Response

Regional Variability in Side-Effects and Steroid Pharmacokinetics

  • Book
  • © 1994

Overview

Editors:
  1. Rachel Snow

    1. Department of Population and International Health, Harvard School of Public Health, Boston, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Peter Hall

    1. World Health Organization, Geneva 27, Switzerland

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Reproductive Biology (RBIO)

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Table of contents (24 chapters)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. Why Pharmacokinetics? An Introduction And Overview

    • Rachel C. Snow, Lucy E. Wilson
    Pages 1-7

  3. Selection of a Contraceptive: What Guides A Woman?

    • Pramilla Senanayake
    Pages 9-14

  4. Contraceptives and Women’s Complaints &— Preliminary Results From the Post-Marketing Surveillance of Norplant R

    • Y. Ahmed, S. Boccard, T. Farley, O. Meirik
    Pages 15-26

  5. Regional and Individual Variation in Bleeding Patterns Associated with Steroid Contraception

    • Elizabeth M. Belsey
    Pages 27-53

  6. Variability in Menstrual Bleeding Patterns: Comparing Treated and Untreated Menstrual Cycles

    • Sioḃán D. Harlow
    Pages 55-59

  7. Contraceptive Use and Discontinuation: The Social Meaning of Side-Effects

    • Carla Makhlouf Obermeyer
    Pages 61-68

  8. Population and Delivery Systems: Variability in Pharmacokevettcs of Long-Acting Injectable Contraceptives

    • Josue Garza-Flores, Sang Guo-Wei, Peter E. Hall
    Pages 69-83

  9. Pharmacology of The Ethynyl Estrogens in Various Countries

    • Joseph W. Goldzieher
    Pages 85-89

  10. Pharmacodynamics of Norplant R Implants

    • Harold A. Nash, Dale N. Robertson
    Pages 91-102

  11. Pharmacokinetic Drug Interactions with Oral Contraceptives

    • D. J. Back, M. L’E. Orme
    Pages 103-123

  12. A Critical Evaluation of the Pharmacokinetics of Contraceptive Steroids

    • Kenneth Fotherby
    Pages 125-132

  13. A Short Review on the Sources of Variability in Pharmacokinetic Parameters of Sex Steroids: Comment on the Paper by K. Fotherby

    • Michael Hümpel
    Pages 133-141

  14. Diet and Estrogen Metabolism

    • Christopher Longcope
    Pages 143-151

  15. Diet, Circulating Estrogen Levels and Estrogen Excretion

    • Barry R. Goldin
    Pages 153-169

  16. Variations in Estrogen Metabolism

    • Leon Bradlow
    Pages 171-177

  17. Body Fat, Fat Topography and Endogenous Steroid Dynamics

    • Rachel Snow
    Pages 179-186

  18. Steroid Contraceptives and Women’s Response: Program Considerations from the Quality of Care Perspective

    • Joan Kaufman
    Pages 187-197

  19. Bringing a Client and Life-Cycle Perspective to Scientific Evidence

    • Judith Bruce
    Pages 199-205

  20. Commentary on Presentation of Dr. Pramilla Senanayake

    • Gary S. Grubb
    Pages 207-211
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Keywords

About this book

Pharmacokinetic variability of contraceptive steroids is a relatively under-explored area of contraceptive research, and hardly a common point of discussion among those who plan and deliver family planning services. Nevertheless, numerous independent studies over the last 15 years have indicated that women in different regions of the world vary in their pharmacokinetic response to contraceptive steroids. The causes of such variability are not known, but it has important consequences for contraceptive effectiveness. It may also offer insight to the basis of contraceptive side-effects. The impetus for this volume was to collect documentation of pharmacokinetic variability of contraceptive steroids, and to explore both the possible causes and implications of these data. Factors known to affect steroid pharmacokinetics, such as concurrent use of specific medications, are reviewed by Back and Orme. Other factors known to affect endogenous steroid dynamics are presented in chapters by Bradlow, Longcope, Goldin and Snow, because of their possible role in contraceptive steroid pharmacokinetics.

Editors and Affiliations

  • Department of Population and International Health, Harvard School of Public Health, Boston, USA

    Rachel Snow

  • World Health Organization, Geneva 27, Switzerland

    Peter Hall

Bibliographic Information

  • Book Title: Steroid Contraceptives and Women’s Response

  • Book Subtitle: Regional Variability in Side-Effects and Steroid Pharmacokinetics

  • Editors: Rachel Snow, Peter Hall

  • Series Title: Reproductive Biology

  • DOI: https://doi.org/10.1007/978-1-4615-2445-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1994

  • Hardcover ISBN: 978-0-306-44718-1Published: 31 July 1994

  • Softcover ISBN: 978-1-4613-6039-1Published: 23 October 2012

  • eBook ISBN: 978-1-4615-2445-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: IX, 266

  • Topics: Pharmacology/Toxicology, Public Health, Epidemiology, Developmental Biology

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