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Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2

Basic Science and Clinical Relevance

  • Book
  • © 1998

Overview

Editors:
  1. David A. Sullivan

    1. The Schepens Eye Research Institute, Harvard Medical School, Boston, USA

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  2. Darlene A. Dartt

    1. The Schepens Eye Research Institute, Harvard Medical School, Boston, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Michele A. Meneray

    1. Louisiana State University Medical Center, New Orleans, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 438)

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Table of contents (149 chapters)

  1. Front Matter

    Pages i-xxiii
    Download chapter PDF

  2. Conference Address

    1. A Clinician Looks at the Tearfilm

      • J. Daniel Nelson
      Pages 1-9

  3. Lacrimal Gland: Cellular and Molecular Biology

    1. Influence of Gender, Sex Steroid Hormones, and the Hypothalamic-Pituitary Axis on the Structure and Function of the Lacrimal Gland

      • David A. Sullivan, L. Alexandra Wickham, Eduardo M. Rocha, Robin S. Kelleher, Lilia Aikawa da Silveira, Ikuko Toda
      Pages 11-42

    2. Androgen-Regulated Transcription in the Epithelium of the Rat Lacrimal Gland

      • F. Claessens, H. Vanaken, I. Vercaeren, G. Verrijdt, A. Haelens, E. Schoenmakers et al.
      Pages 43-48

    3. Gene Cloning of BM180, a Lacrimal Gland Enriched Basement Membrane Protein with a Role in Stimulated Secretion

      • Anil C. Asrani, Angela J. Lumsden, Rajesh Kumar, Gordon W. Laurie
      Pages 49-54

    4. Sensory Denervation Leads to Deregulated Protein Synthesis in the Lacrimal Gland

      • Doan H. Nguyen, Roger W. Beuerman, Michele A. Meneray, Dmitri Maitchouk
      Pages 55-62

    5. Acinar Cell Basal-Lateral Membrane—Endomembrane Traffic May Mediate Interactions with Both T Cells and B Cells

      • Austin K. Mircheff, Tao Yang, Jian Zhang, Hongtao Zeng, J. Peter Gierow, Dwight W. Warren et al.
      Pages 63-68

    6. Tissue Expression of Tear Lipocalin in Humans

      • Catherine Ressot, Hervé Lassagne, Jean-Louis Kemeny, Anne-Marie Françoise Gachon
      Pages 69-73

    7. The Exorbital Lacrimal Glands of the Rat are Tensed in Situ

      • Mortimer Lorber
      Pages 75-80

    8. Aberrant Lacrimal Gland Development in an Anophthalmic Mutant Strain of Rat

      • Prabir K. De
      Pages 81-84

    9. Hormonal Influences on Syrian Hamster Lacrimal Gland

      • Prabir K. De, Velvizhi Ranganathan
      Pages 85-88

    10. Androgen Support of Lacrimal Gland Function in the Female Rabbit

      • Dwight W. Warren, Ana Maria Azzarolo, Zuo Ming Huang, Barbara W. Platler, Renee L. Kaswan, Elizabeth Gentschein et al.
      Pages 89-93

    11. Identification and Hormonal Control of Sex Steroid Receptors in the Eye

      • L. Alexandra Wickham, Eduardo M. Rocha, Jianping Gao, Kathleen L. Krenzer, Lilia Aikawa da Silveira, Ikuko Toda et al.
      Pages 95-100

    12. Dinucleotide Repeat Polymorphism Near the Tear Lipocalin Gene

      • Eric Lacazette, Gilles Pitiot, Jacques Mallet, Anne-Marie Françoise Gachon
      Pages 101-103

    13. Studies of Ligand Binding and CD Analysis with Apo- and Holo-Tear Lipocalins

      • Ben J. Glasgow, Adil R. Abduragimov, Taleh N. Yusifov, Oktai K. Gasymov
      Pages 105-112

  4. Lacrimal Gland and Ocular Surface: Signal Transduction, Membrane Traffic, and Fluid and Protein Secretion

    1. Signal Transduction Pathways Activated by Cholinergic and α1-Adrenergic Agonists in the Lacrimal Gland

      • Darlene A. Dartt, Robin R. Hodges, Driss Zoukhri
      Pages 113-121

    2. Calcium Signalling in Lacrimal Acinar Cells

      • James W. Putney Jr., Yi Huang, Gary St. J. Bird
      Pages 123-128

    3. Voltage- and Ca2+-Dependent Chloride Current Activated by Hyposmotic and Hyperosmotic Stress in Rabbit Superior Lacrimal Acinar Cells

      • George H. Herok, Thomas J. Millar, Philip JnA Derton, Donald K. Martin
      Pages 129-132

    4. G Protein Coupling of Receptor Activation to Lacrimal Secretion

      • Michele A. Meneray, Tammy Y. Fields
      Pages 133-138

    5. Microtubules and Intracellular Traffic of Secretory Proteins in Rat Extraorbital Lacrimal Glands

      • Philippe Robin, Marie-Noëlle Raymond, Bernard Rossignol
      Pages 139-144
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Keywords

About this book

During the past two decades, a significant international research effort has been di­ rected toward understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays an essential role in maintaining corneal and conjunctival integrity, protecting against microbial challenge, and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in countless individuals throughout the world, may lead to desiccation of the ocular surface, ulceration and perfo­ ration of the cornea, an increased incidence of infectious disease, and, potentially, pro­ nounced visual disability and blindness. To promote further progress in this field of vision research, the Second International Conference on the Lacrimal Gland, Tear Film and Dry Eye Syndromes: Basic Science and Clinical Relevance was held at the Southampton Princess Resort in Bermuda November 16-19, 1996. This conference was organized and directed by David A. Sullivan, Ph. D. , codirected by Darlene A. Dartt, Ph. D. , and Michele A. Meneray, Ph. D. , and sponsored by the Schepens Eye Research Institute (Boston, MA), an affiliate of Harvard Medical School. The meeting was designed to assess critically the current knowledge and "state of the art" research on the structure and function of lacrimal tissue, tears, and the ocular sur­ face in both health and disease.

Editors and Affiliations

  • The Schepens Eye Research Institute, Harvard Medical School, Boston, USA

    David A. Sullivan, Darlene A. Dartt

  • Louisiana State University Medical Center, New Orleans, USA

    Michele A. Meneray

Bibliographic Information

  • Book Title: Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2

  • Book Subtitle: Basic Science and Clinical Relevance

  • Editors: David A. Sullivan, Darlene A. Dartt, Michele A. Meneray

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-5359-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1998

  • Hardcover ISBN: 978-0-306-45812-5Due: 31 May 1998

  • Softcover ISBN: 978-1-4613-7445-9Published: 23 May 2013

  • eBook ISBN: 978-1-4615-5359-5Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XXIII, 1051

  • Topics: Ophthalmology, Animal Anatomy / Morphology / Histology, Biological and Medical Physics, Biophysics

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