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Methods in Molecular Biology

Computational Methods for Drug Repurposing

Editors: Vanhaelen, Quentin (Ed.)

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  • Includes cutting-edge techniques
  • Provides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts
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eBook $169.00
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  • ISBN 978-1-4939-8955-3
  • Digitally watermarked, DRM-free
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Hardcover $219.99
price for USA
  • ISBN 978-1-4939-8954-6
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  • Covid-19 shipping restrictions
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About this book

This detailed book explores techniques commonly used for research into drug repurposing, a well-known strategy to find alternative indications for drugs which have already undergone toxicology and pharma-kinetic studies but have failed later stages during the development, via computational methods. Thereby, it addresses the intense challenges of identifying the appropriate type of algorithm and relevant technical information for computational repurposing. Written for the highly successful Methods in Molecular Biology series, the authors of each chapter use their experience in the field to describe the implementation and successful use of a specific repurposing method thus providing lab-ready instruction. 
Authoritative and practical, Computational Methods for Drug Repurposing serves as an ideal guide to researchers interested in this vital area of drug development.

Table of contents (19 chapters)

Table of contents (19 chapters)
  • Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing

    Pages 1-21

    Ozdemir, E. Sila (et al.)

  • Performing an In Silico Repurposing of Existing Drugs by Combining Virtual Screening and Molecular Dynamics Simulation

    Pages 23-43

    Sohraby, Farzin (et al.)

  • Repurposing Drugs Based on Evolutionary Relationships Between Targets of Approved Drugs and Proteins of Interest

    Pages 45-59

    Chakraborti, Sohini (et al.)

  • Drug Repositioning by Mining Adverse Event Data in ClinicalTrials.gov

    Pages 61-72

    Su, Eric Wen

  • Transcriptomic Data Mining and Repurposing for Computational Drug Discovery

    Pages 73-95

    Wang, Yunguan (et al.)

Buy this book

eBook $169.00
price for USA
  • ISBN 978-1-4939-8955-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA
  • ISBN 978-1-4939-8954-6
  • with online files
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock

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Bibliographic Information

Bibliographic Information
Book Title
Computational Methods for Drug Repurposing
Editors
  • Quentin Vanhaelen
Series Title
Methods in Molecular Biology
Series Volume
1903
Copyright
2019
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-8955-3
DOI
10.1007/978-1-4939-8955-3
Hardcover ISBN
978-1-4939-8954-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 332
Number of Illustrations
21 b/w illustrations, 82 illustrations in colour
Topics