Methods in Molecular Biology

Genotoxicity Assessment

Methods and Protocols

Editors: Dhawan, Alok, Bajpayee, Mahima (Eds.)

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  • Includes cutting-edge techniques
  • Provides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts
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eBook $169.00
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  • ISBN 978-1-4939-9646-9
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Hardcover $219.99
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About this book

This current edition explores new tests for genotoxicity testing, along with other well-known techniques. This will further help in our understanding of the genotoxic effects of chemicals. The book has different sections dealing with various assays for gene mutation, chromosomal abnormalities, primary DNA damage, etc. It also delves into plant models, animals and their alternates, as well as in silico approaches for genetic toxicology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, tips on troubleshooting and avoiding known pitfalls. 
Authoritative and up-to-date, Genotoxicity Assessment: Methods and Protocols, Second Edition serves as a highly useful and ready resource for research students and scientists working in regulatory toxicology as well as biomedical, biochemical, and pharmaceutical sciences.

Table of contents (20 chapters)

Table of contents (20 chapters)
  • In Vitro Mouse Lymphoma Cell (L5178Y Tk+/− −3.7.2.C) Forward Mutation Assay

    Pages 3-28

    Schisler, Melissa R. (et al.)

  • Erythrocyte-Based Pig-a Gene Mutation Assay

    Pages 29-57

    Bemis, Jeffrey C. (et al.)

  • Detection of In Vivo Mutation in the Hprt and Pig-a Genes of Rat Lymphocytes

    Pages 59-75

    Dobrovolsky, Vasily N. (et al.)

  • In Vitro Cytogenetic Assays: Chromosomal Aberrations and Micronucleus Tests

    Pages 79-104

    Mosesso, Pasquale (et al.)

  • Dicentric Chromosome Assay (DCA) and Cytokinesis-Block Micronucleus (CBMN) Assay in the Field of Biological Dosimetry

    Pages 105-119

    Testa, Antonella (et al.)

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-1-4939-9646-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA
  • ISBN 978-1-4939-9645-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.

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Bibliographic Information

Bibliographic Information
Book Title
Genotoxicity Assessment
Book Subtitle
Methods and Protocols
Editors
  • Alok Dhawan
  • Mahima Bajpayee
Series Title
Methods in Molecular Biology
Series Volume
2031
Copyright
2019
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-4939-9646-9
DOI
10.1007/978-1-4939-9646-9
Hardcover ISBN
978-1-4939-9645-2
Series ISSN
1064-3745
Edition Number
2
Number of Pages
XI, 378
Number of Illustrations
37 b/w illustrations, 57 illustrations in colour
Topics