Skip to main content
  • Book
  • © 2014

G Protein-Coupled Receptor Genetics

Research and Methods in the Post-Genomic Era

  • Explores the powerful and versatile g protein-coupled receptors and their application in health and medicine
  • Features practical methods that are lab-proven and ready to use
  • Includes expert opinions on the future directions of the rapidly progressing field
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Pharmacology and Toxicology (MIPT)

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (21 protocols)

  1. Front Matter

    Pages i-xi
  2. Genetic Mechanisms of G Protein-Coupled Receptors

    1. Front Matter

      Pages 1-1
    2. Examining the Dynamic Evolution of G Protein-Coupled Receptors

      • Claudia Stäubert, Diana Le Duc, Torsten Schöneberg
      Pages 23-43
    3. Discovery and Function of the Very Large G Protein-Coupled Receptor

      • Perrin C. White, D. Randy McMillan
      Pages 67-83
    4. Functional Evolution of Opioid Family G Protein-Coupled Receptors

      • Eyal Vardy, Craig W. Stevens, Bryan L. Roth
      Pages 85-104
    5. Signalosome Profiling Reveals Allosteric Interactions Between G Protein-Coupled Receptors

      • Katrin Altosaar, Darlaine Pétrin, Dominic Devost, Terence E. Hébert
      Pages 127-146
  3. Genetic Toolbox for G Protein-Coupled Receptor Discovery

    1. Front Matter

      Pages 147-147
    2. Use of Optogenetic Approaches to Control Intracellular Signaling of G Protein-Coupled Receptors

      • Olivia A. Masseck, Melanie D. Mark, Stefan Herlitze
      Pages 149-160
    3. Viral Infection for G Protein-Coupled Receptor Expression in Eukaryotic Cells

      • Antonio Porcellini, Luisa Iacovelli, Antonio De Blasi
      Pages 161-175
    4. The CRE Luc Mouse Model for Bioimaging Ligand Activation of G Protein-Coupled Receptors

      • H. Gregory Polites, Kyriakos D. Economides
      Pages 197-217
    5. Rescue of Defective G Protein-Coupled Receptor Function by Intermolecular Cooperation

      • Ashutosh Trehan, Kim Carol Jonas, Ilpo Huhtaniemi, Aylin Carla Hanyaloglu, Adolfo Rivero-Müller
      Pages 239-255
  4. Genetic Aspects of G Protein-Coupled Receptors in Health and Medicine

    1. Front Matter

      Pages 287-287
    2. Pharmacogenomics of G Protein-Coupled Receptor Signaling and Other Pathways in Essential Hypertension

      • Pedro A. Jose, Van Anthony M. Villar, Matthew R. Weir, Robin A. Felder
      Pages 299-312

About this book

G ProteinCoupled Receptor Genetics: Research and Methods in the PostGenomic Era features practical techniques inspired by the fast moving GPCR field. From powerful bioinformatic tools tracing the evolution of GPCRs, to methods for the cellular transfection of engineered viruses containing GPCRs, to optogenetic techniques that produce light-activated GPCRs in live mice, what was once science fiction is now science fact. This detailed volume includes sections covering genetic mechanisms, a genetic toolbox for GPCR discovery, as well as genetic aspects of G protein-coupled receptors in health and medicine. Written for the Methods in Pharmacology and Toxicology series, this book contains the kind of key implementation advice that encourages successful results in the lab.

Authoritative and easy to use, G ProteinCoupled Receptor Genetics: Research and Methods in the PostGenomic Era serves as an ideal guide for researchers aiming to continue our progress in this dynamic and exciting area of study.

Editors and Affiliations

  • Oklahoma State University, Tulsa, USA

    Craig W. Stevens

Bibliographic Information

  • Book Title: G Protein-Coupled Receptor Genetics

  • Book Subtitle: Research and Methods in the Post-Genomic Era

  • Editors: Craig W. Stevens

  • Series Title: Methods in Pharmacology and Toxicology

  • DOI: https://doi.org/10.1007/978-1-62703-779-2

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-62703-778-5Published: 24 January 2014

  • Softcover ISBN: 978-1-4939-6332-4Published: 17 September 2016

  • eBook ISBN: 978-1-62703-779-2Published: 24 January 2014

  • Series ISSN: 1557-2153

  • Series E-ISSN: 1940-6053

  • Edition Number: 1

  • Number of Pages: XI, 423

  • Number of Illustrations: 26 b/w illustrations, 40 illustrations in colour

  • Topics: Pharmacology/Toxicology, Proteomics

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access