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Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders

Editors:

  • The book considers both successful and failed attempts at biomarker-based approaches in psychiatry and thereby gives balanced review of the field
  • It covers a wide range of techniques from the 'omics to imaging-based methods and discusses the strategies behind their use
  • It describes in detail the latest biomarker approaches for the near future approaching personalised medicine
  • The contributions come from researchers from 5 out of the 6 habitable continents, indicative of the global concern in this area

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1118)

Part of the book sub series: Proteomics, Metabolomics, Interactomics and Systems Biology (PMISB)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xiii
  2. Genetic Risk Factors for Alzheimer Disease: Emerging Roles of Microglia in Disease Pathomechanisms

    • Sho Takatori, Wenbo Wang, Akihiro Iguchi, Taisuke Tomita
    Pages 83-116
  3. Neuroimaging Studies of Cognitive Function in Schizophrenia

    • Rafael Penadés, Nicolas Franck, Laura González-Vallespí, Marie Dekerle
    Pages 117-134
  4. The Role of Biomarkers in Psychiatry

    • Madia Lozupone, Maddalena La Montagna, Francesca D’Urso, Antonio Daniele, Antonio Greco, Davide Seripa et al.
    Pages 135-162
  5. Interactome Studies of Psychiatric Disorders

    • Dong Ik Park, Christoph W. Turck
    Pages 163-173
  6. MicroRNAs in Major Depressive Disorder

    • Gabriel R. Fries, Wei Zhang, Deborah Benevenuto, Joao Quevedo
    Pages 175-190
  7. Proteomic Markers for Depression

    • Licia C. Silva-Costa, Pamela T. Carlson, Paul C. Guest, Valéria de Almeida, Daniel Martins-de-Souza
    Pages 191-206
  8. Advances in Biomarker Studies in Autism Spectrum Disorders

    • Liming Shen, Yuxi Zhao, Huajie Zhang, Chengyun Feng, Yan Gao, Danqing Zhao et al.
    Pages 207-233
  9. Role of the Gut Microbiome in Autism Spectrum Disorders

    • Joby Pulikkan, Agnisrota Mazumder, Tony Grace
    Pages 253-269
  10. Metabolomic Biomarkers in Mental Disorders: Bipolar Disorder and Schizophrenia

    • Melissa Quintero, Danijela Stanisic, Guilherme Cruz, João G. M. Pontes, Tássia Brena Barroso Carneiro Costa, Ljubica Tasic
    Pages 271-293
  11. Back Matter

    Pages 319-328

About this book

This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing a viable mechanism of catching up with other areas of modern medicine, such as diabetes and heart disease. Finally, it is anticipated that the development and application of valid biomarker tests and the leveraging of novel drug targets will help the fields of psychiatry on neurodegenerative disorders move into the area of personalized medicine where the right patients can receive the right medication at the right time for the best possible outcome.

Editors and Affiliations

  • Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil

    Paul C. Guest

About the editor

Dr Paul C. Guest, Ph.D, is a scientific researcher/writer with 35 years of experience in the fields of metabolic and neurological disorders. This includes experience in both academia and the pharmaceutical industry with the majority of time spent at the University of Cambridge and Merck Sharp & Dohme in the United Kingdom. He has also been affiliated with the University of Campinas in Sao Paulo Brazil since 2015, still focused on advancing the field of biomarkers for neurological disorders such as schizophrenia and Alzheimer’s disease.

Bibliographic Information

  • Book Title: Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders

  • Editors: Paul C. Guest

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-030-05542-4

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-05541-7Published: 21 February 2019

  • eBook ISBN: 978-3-030-05542-4Published: 12 February 2019

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIII, 328

  • Number of Illustrations: 2 b/w illustrations, 26 illustrations in colour

  • Topics: Systems Biology, Proteomics, Gene Expression

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access