Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders
Editors: Guest, Paul C. (Ed.)
Free Preview- Discusses both positive and negative findings
- Describes studies of diseases not commonly thought of as having metabolic links or origins
- Looks at economic aspects of these diseases and the benefits of using biomarkers for the healthcare systems
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- About this book
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The book recognizes that throughout the scientific, medical, and economic communities, new tests incorporating biomarkers are needed to improve the diagnosis of patients suffering from metabolic disorders. The early identification of those at risk of developing obesity will help to place these individuals on the best treatment course as early as possible for improved treatment outcomes. This will also help to cut costs incurred by the healthcare services. For all of this to occur, new research efforts are needed to identify novel biomarkers that can be used to predict the disease in the presymptomatic stage, for disease monitoring and for prediction of treatment response. It is also possible that new drug targets can be identified using these approaches which, in turn, can lead to the development of new treatment approaches. This volume also includes a series of reviews on biomarker discovery and usage in the study of diseases marked by perturbations in metabolism. It will describe the pros and cons of the various approaches and cover the successes and failures in this important research field.
- About the authors
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Dr Paul C. Guest, Ph.D, is a scientific researcher/writer with 35 years of experience in the fields of metabolic and neurological disorders. This includes experience in both academia and the pharmaceutical industry with the majority of time spent at the University of Cambridge and Merck Sharp & Dohme in the United Kingdom. He has also been affiliated with the University of Campinas in Sao Paulo Brazil since 2015, still focused on advancing the field of biomarkers for neurological disorders such as schizophrenia and Alzheimer’s disease.
- Table of contents (15 chapters)
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Insulin Resistance in Schizophrenia
Pages 1-16
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Biogenesis of the Insulin Secretory Granule in Health and Disease
Pages 17-32
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Current Models of Fatty Liver Disease; New Insights, Therapeutic Targets and Interventions
Pages 33-58
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Preclinical Models of Altered Early Life Nutrition and Development of Reproductive Disorders in Female Offspring
Pages 59-87
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Targeting Mitochondrial Defects to Increase Longevity in Animal Models of Neurodegenerative Diseases
Pages 89-110
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Table of contents (15 chapters)
Bibliographic Information
- Bibliographic Information
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- Book Title
- Reviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders
- Editors
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- Paul C. Guest
- Series Title
- Proteomics, Metabolomics, Interactomics and Systems Biology
- Series Volume
- 1134
- Copyright
- 2019
- Publisher
- Springer International Publishing
- Copyright Holder
- Springer Nature Switzerland AG
- eBook ISBN
- 978-3-030-12668-1
- DOI
- 10.1007/978-3-030-12668-1
- Hardcover ISBN
- 978-3-030-12667-4
- Softcover ISBN
- 978-3-030-12670-4
- Series ISSN
- 2730-6216
- Edition Number
- 1
- Number of Pages
- XI, 303
- Number of Illustrations
- 17 b/w illustrations, 22 illustrations in colour
- Topics
