Meningiomas

1. Front Matter

   Pages i-xiii

   PDF

2. Meningioma Basics

   1. Front Matter

      Pages 1-1

      PDF

   2. An Overview of Meningiomas

      • Michel Kalamarides, Matthieu Peyre

      Pages 3-10

   3. Histopathology and Grading of Meningiomas

      • Declan McGuone, Anita Huttner

      Pages 11-24

   4. Radiographic Assessment of Meningiomas

      • Thomas J. Kaley

      Pages 25-33

   5. The Genomic Landscape of Meningiomas

      • Amy Y. Zhao, Mark W. Youngblood, E. Zeynep Erson-Omay, Jennifer Moliterno, Murat Gunel

      Pages 35-55

3. Initial Meningioma Management and Treatment Paradigms

   1. Front Matter

      Pages 57-57

      PDF

   2. The Initial Evaluation and Surveillance of Meningiomas

      • Isabel P. Prado, Zachary A. Corbin

      Pages 59-73

   3. Surgical Considerations for Newly Diagnosed Meningiomas

      • Christopher S. Hong, Jennifer Moliterno

      Pages 75-96

   4. Endoscopic and Minimally Invasive Meningioma Surgery

      • S. Bulent Omay, Theodore H. Schwartz

      Pages 97-108

   5. Comprehensive Treatment Strategies for Spinal Meningiomas

      • Robert J. Rothrock, Ori Barzilai, Yoshiya (Josh) Yamada, Mark H. Bilsky

      Pages 109-123

   6. Radiation Therapy for Low Grade Meningiomas

      • Gabrielle W. Peters, Joseph N. Contessa

      Pages 125-144

4. Treatment Options for more aggressive meningiomas

   1. Front Matter

      Pages 145-145

      PDF

   2. Low Grade Tumor Recurrence and Management of More Aggressive Meningiomas

      • Daniel M. Fountain, Thomas Santarius

      Pages 147-159

   3. Surgical Considerations for Recurrent Meningiomas

      • Amol Raheja, William T. Couldwell

      Pages 161-173

   4. Radiotherapy for Aggressive Meningiomas and Recurrent Low Grade Tumors

      • Diana A. Roth O’Brien, Swathi Chidambaram, Sean S. Mahase, Jana Ivanidze, Susan C. Pannullo

      Pages 175-200

   5. The Role of Medical Therapy for Menigniomas

      • Ashley M. Roque, Antonio Omuro

      Pages 201-215

   6. Emerging Meningioma Therapies I: Precision Medicine, Targeted Therapies, and Mutation-Specific Approaches

      • Ashley M. Roque, Antonio Omuro

      Pages 217-226

   7. Emerging Meningioma Therapies II: Immunotherapies, Novel Radiotherapy Techniques, and Other Experimental Approaches

      • Corey M. Gill, Priscilla K. Brastianos

      Pages 227-238

5. Back Matter

   Pages 239-243

   PDF

This book provides a comprehensive overview of the multidisciplinary management of meningiomas, followed by evaluation and management considerations along a spectrum of benign to more malignant behavior. It outlines the management of presumed Grade 1 tumors and how to identify features of tumors radiographically and clinically that may support a benign course rather than aggressive and vice versa. Following a stepwise progression from simple to complex, chapters introduce and tackle more aggressive meningiomas and tumor recurrence (of all Grades), with paradigms for evaluation and treatment. Tumor biology and genomics are fundamental and largely focused in the book. More recent findings which have directed personalized medicine and clinical trials are also addressed. 


Meningiomas: Comprehensive Strategies for Management addresses all aspects of the evaluation and care of patients with all WHO grades of meningiomas. It is highly informative and provides clarity for a wide audience of neurosurgeons, reconstructive surgeons, oncologists, neurologists, radiation oncologists, pathologists, radiologists, residents and students who treat these patients and those who are training for a career in managing patients with these potentially challenging tumors.

• intraventricular
• cranio-cervical junction
• LITT
• Immunotherapy
• Yttrium Y 90
• Radiaton Oncology

• Department of Neurosurgery, Yale School of Medicine, Yale New Haven Hospital, New Haven, USA

  Jennifer Moliterno

• Department of Neurology, Yale School of Medicine, Yale New Haven Hospital, New Haven, USA

  Antonio Omuro

Jennifer Moliterno
Chief of Neurosurgical Oncology, Yale New Haven Hospital and Smilow Cancer Hospital
Co-Director, Yale Brain Tumor Center at Smilow Cancer Hospital
Associate Professor, Department of Neurosurgery, Yale School of Medicine, Yale University
Department of Neurosurgical Oncology
Yale School of Medicine
New Haven, CT
USA






Antonio Omuro
Chief of Neuro-Oncology, Yale New Haven Hospital and Smilow Cancer Hospital
Director, Yale Brain Tumor Center at Smilow Cancer Hospital
Professor, Department of Neurology Yale School of Medicine, Yale University
New Haven, CT
USA

Policies and ethics