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Antiseizure Medication Interactions

A Clinical Guide

  • Includes details of the magnitude and mechanism of relevant interactions

  • Discusses the uses of new agents including cannabidiol and cenobamate

  • Features relevant data on the topics covered

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Table of contents (75 chapters)

  1. Front Matter

    Pages i-xv
  2. Part I

    1. Front Matter

      Pages 1-5
    2. Introduction

      • Philip N. Patsalos
      Pages 7-30
    3. Acetazolamide

      • Philip N. Patsalos
      Pages 31-33
    4. Brivaracetam

      • Philip N. Patsalos
      Pages 35-38
    5. Cannabidiol

      • Philip N. Patsalos
      Pages 39-42
    6. Carbamazepine

      • Philip N. Patsalos
      Pages 43-49
    7. Cenobamate

      • Philip N. Patsalos
      Pages 51-54
    8. Clobazam

      • Philip N. Patsalos
      Pages 55-59
    9. Clonazepam

      • Philip N. Patsalos
      Pages 61-64
    10. Eslicarbazepine Acetate

      • Philip N. Patsalos
      Pages 65-68
    11. Ethosuximide

      • Philip N. Patsalos
      Pages 69-72
    12. Everolimus

      • Philip N. Patsalos
      Pages 73-76
    13. Felbamate

      • Philip N. Patsalos
      Pages 77-80
    14. Fenfluramine

      • Philip N. Patsalos
      Pages 81-84
    15. Gabapentin

      • Philip N. Patsalos
      Pages 85-87
    16. Lacosamide

      • Philip N. Patsalos
      Pages 89-92
    17. Lamotrigine

      • Philip N. Patsalos
      Pages 93-97
    18. Levetiracetam

      • Philip N. Patsalos
      Pages 99-102
    19. Methsuximide

      • Philip N. Patsalos
      Pages 103-106

About this book

This significantly revised fourth edition provides a practically orientated guide to interactions associated with antiseizure medications. It describes pharmacokinetic and pharmacodynamic antiseizure medication (ASM) interactions, including details of the magnitude and mechanism of interactions, and also of drug combinations that are not associated with interactions and therefore can be co-prescribed without undue concern.

 Presented in alphabetical order and by drug class, drug interactions that occur between ASMs and also between ASMs and non- ASMs are described in three sections: Drug interactions between ASMs; Drug interactions between ASMs and non- ASM Drugs: Interactions affecting ASMs; Drug interactions between ASMs and non ASM Drugs: Interactions affected by ASMs. The latest data on all drug interactions is presented. New agents discussed include cannabidiol, cenobamate, everolimus and fenfluramine,.

Antiseizure Medication Interactions: A Clinical Guide, 4th Edition concisely presents the most recent developments and data available on the topic. Therefore, enabling physicians and allied health professionals to make more rational choices when ASM polytherapy regimens are required. It will be of interest to medical professionals in disciplines including neurology, psychiatry and pediatrics. 

Authors and Affiliations

  • Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, UK

    Philip N. Patsalos

About the author

Philip Patsalos is an Emeritus Professor of Clinical Pharmacology at University College London's Queen Square Institute of Neurology, Department of Clinical and Experimental Epilepsy, London UK. His clinical and research interests relate to the therapeutics of epilepsy and include: new drug treatments and strategies, new drug development (Phase II and III trials) and formulations, pharmacokinetic profiling and drug interactions. He has in excess of 230 publications (books, book chapters and peer reviewed papers) and has served on various International League Against Epilepsy (ILAE) committees (including the Commission on Therapeutic Strategies, the Commission on Generics, the Sub-Commission on Polytherapy and Drug Interaction and the Sub-Commission on Therapeutic Drug Monitoring) and International Association of Therapeutic Drug Monitoring and Clinical Toxicology committees (including the Clinical Pharmacokinetics Committee and the Impact of Therapeutic Drug Monitoring on Pharmacoeconomics Committee). He was recently awarded the 2016 Excellence in Epilepsy Lifetime Achievement Award by the British Branch ILAE for his contribution to epilepsy care and research.

 

Bibliographic Information

  • Book Title: Antiseizure Medication Interactions

  • Book Subtitle: A Clinical Guide

  • Authors: Philip N. Patsalos

  • DOI: https://doi.org/10.1007/978-3-030-82790-8

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Softcover ISBN: 978-3-030-82789-2Published: 02 January 2022

  • eBook ISBN: 978-3-030-82790-8Published: 01 January 2022

  • Edition Number: 4

  • Number of Pages: XV, 357

  • Number of Illustrations: 32 b/w illustrations

  • Topics: Neurology, Pharmacology/Toxicology, Psychiatry

Buy it now

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access