- Is the first thematic book about proteogenomics
- Provides front line information on both genomic, transcriptomic and proteomic research and a novel, combined view
- Gives an overview of each scientific area supported by applications in disease research
Buy this book
- About this book
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This book highlights key technologies and identifies areas for further development in proteogenomics. The utility and usefulness of very large Omics data sets (Next Gen Sequencing of DNA, RNA-seq, ribosome profiling, mass spectrometry- and antibody-based proteomics) is discussed and opportunities and challenges of related bioinformatics applications are outlined.
The reader will be able to appreciate the interdisciplinary nature of the continuously evolving area of proteogenomics, which has already grown beyond its original concept of verifying gene annotations by proteomics. The chapters presented in this book are arranged to offer a general overview, rather than to provide detailed descriptions of technologies. The selected applications will provide useful insight into the level of detail that can be obtained in relation to certain diseases areas, including cancer biology and personalized medicine. The readers will find that each chapter delivers a comprehensive approach to proteogenomics, each from the point of view of a specific application.
Research scientists interested in innovative processes that can offer a unique and at the same time a more complete access to technological developments and concepts that in turn can contribute to a better understand biological functions should read this book.
- Table of contents (11 chapters)
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Proteogenomic Tools and Approaches to Explore Protein Coding Landscapes of Eukaryotic Genomes
Pages 1-10
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Next Generation Sequencing Data and Proteogenomics
Pages 11-19
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Proteogenomics: Key Driver for Clinical Discovery and Personalized Medicine
Pages 21-47
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Identification of Small Novel Coding Sequences, a Proteogenomics Endeavor
Pages 49-64
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Using Proteomics Bioinformatics Tools and Resources in Proteogenomic Studies
Pages 65-75
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Table of contents (11 chapters)
Bibliographic Information
- Bibliographic Information
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- Book Title
- Proteogenomics
- Editors
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- Ákos Végvári
- Series Title
- Advances in Experimental Medicine and Biology
- Series Volume
- 926
- Copyright
- 2016
- Publisher
- Springer International Publishing
- Copyright Holder
- Springer International Publishing Switzerland
- eBook ISBN
- 978-3-319-42316-6
- DOI
- 10.1007/978-3-319-42316-6
- Hardcover ISBN
- 978-3-319-42314-2
- Softcover ISBN
- 978-3-319-82551-9
- Series ISSN
- 0065-2598
- Edition Number
- 1
- Number of Pages
- VIII, 184
- Number of Illustrations
- 2 b/w illustrations, 55 illustrations in colour
- Topics
