Overview
- Is the first thematic book about proteogenomics
- Provides front line information on both genomic, transcriptomic and proteomic research and a novel, combined view
- Gives an overview of each scientific area supported by applications in disease research
- Includes supplementary material: sn.pub/extras
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 926)
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Table of contents (11 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book highlights key technologies and identifies areas for further development in proteogenomics. The utility and usefulness of very large Omics data sets (Next Gen Sequencing of DNA, RNA-seq, ribosome profiling, mass spectrometry- and antibody-based proteomics) is discussed and opportunities and challenges of related bioinformatics applications are outlined.
The reader will be able to appreciate the interdisciplinary nature of the continuously evolving area of proteogenomics, which has already grown beyond its original concept of verifying gene annotations by proteomics. The chapters presented in this book are arranged to offer a general overview, rather than to provide detailed descriptions of technologies. The selected applications will provide useful insight into the level of detail that can be obtained in relation to certain diseases areas, including cancer biology and personalized medicine. The readers will find that each chapter delivers a comprehensive approach to proteogenomics, each from the point of view of a specific application.
Research scientists interested in innovative processes that can offer a unique and at the same time a more complete access to technological developments and concepts that in turn can contribute to a better understand biological functions should read this book.
Editors and Affiliations
Bibliographic Information
Book Title: Proteogenomics
Editors: Ákos Végvári
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-319-42316-6
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016
Hardcover ISBN: 978-3-319-42314-2Published: 12 October 2016
Softcover ISBN: 978-3-319-82551-9Published: 27 June 2018
eBook ISBN: 978-3-319-42316-6Published: 29 September 2016
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VIII, 184
Number of Illustrations: 2 b/w illustrations, 55 illustrations in colour
Topics: Proteomics, Gene Function, Mass Spectrometry, Gene Expression