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Current Topics in Microbiology and Immunology

The Actin Cytoskeleton and Bacterial Infection

Editors: Mannherz, Hans Georg (Ed.)

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  • Presents a comprehensive overview of the actin modifying actions of bacterial toxins
  •  Bridges the gap between common knowledge, new findings and new concepts for therapeutic approaches
  •  A valuable resource for microbiologists, cell biologists, and clinicians whose work involves infectious diseases 
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eBook $149.00
price for USA (gross)
  • ISBN 978-3-319-50047-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
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  • Immediate eBook download after purchase
Hardcover $199.99
price for USA
  • ISBN 978-3-319-50046-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA
  • ISBN 978-3-319-84305-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton.
In short, this volume provides an overview of the various tricks bacteria have evolved to “act on actin” in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases.

About the authors

Hans Georg MannherzRuhr-Universität BochumInstitut für AnatomieAbteilung für Anatomie und molekulare Embryologiee-mail: Hans.Mannherz@ruhr-uni-bochum.de

Table of contents (11 chapters)

Table of contents (11 chapters)
  • Actin: Structure, Function, Dynamics, and Interactions with Bacterial Toxins

    Pages 1-34

    Kühn, Sonja (et al.)

  • Formation of Nanotube-Like Protrusions, Regulation of Septin Organization and Re-guidance of Vesicle Traffic by Depolymerization of the Actin Cytoskeleton Induced by Binary Bacterial Protein Toxins

    Pages 35-51

    Schwan, Carsten (et al.)

  • Photorhabdus luminescens Toxins TccC3 and TccC5 Affect the Interaction of Actin with Actin-Binding Proteins Essential for Treadmilling

    Pages 53-67

    Lang, Alexander E. (et al.)

  • Comparative Studies of Actin- and Rho-Specific ADP-Ribosylating Toxins: Insight from Structural Biology

    Pages 69-86

    Tsuge, Hideaki (et al.)

  • Pathogenic Mechanisms of Actin Cross-Linking Toxins: Peeling Away the Layers

    Pages 87-112

    Kudryashova, Elena (et al.)

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-319-50047-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA
  • ISBN 978-3-319-50046-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA
  • ISBN 978-3-319-84305-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.

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Bibliographic Information

Bibliographic Information
Book Title
The Actin Cytoskeleton and Bacterial Infection
Editors
  • Hans Georg Mannherz
Series Title
Current Topics in Microbiology and Immunology
Series Volume
399
Copyright
2017
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing AG
eBook ISBN
978-3-319-50047-8
DOI
10.1007/978-3-319-50047-8
Hardcover ISBN
978-3-319-50046-1
Softcover ISBN
978-3-319-84305-6
Series ISSN
0070-217X
Edition Number
1
Number of Pages
X, 242
Topics