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The Neuropharmacology of Alcohol

  • Book
  • © 2018

Overview

Editors:
  1. Kathleen A. Grant

    1. Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. David M. Lovinger

    1. Laboratory for Integrative Neuroscience, National Institutes of Health, Bethesda, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Provides new insights to alcohol pharmacology using DREADDs
  • Discusses latest techniques that are utilized in the circuitry field
  • Includes very current research extending to the clinic

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 248)

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Table of contents (26 chapters)

  1. Front Matter

    Pages i-xi
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  2. Neurotransmitter Systems

    1. Front Matter

      Pages 1-1
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    2. GABAA Receptor Subtype Mechanisms and the Abuse-Related Effects of Ethanol: Genetic and Pharmacological Evidence

      • Cassie M. Chandler, John S. Overton, Daniela Rüedi-Bettschen, Donna M. Platt
      Pages 3-27

    3. Presynaptic Ethanol Actions: Potential Roles in Ethanol Seeking

      • David M. Lovinger
      Pages 29-54

    4. Dynamic Adaptation in Neurosteroid Networks in Response to Alcohol

      • Deborah A. Finn, Vanessa A. Jimenez
      Pages 55-78

    5. GABA and Glutamate Synaptic Coadaptations to Chronic Ethanol in the Striatum

      • Verginia C. Cuzon Carlson
      Pages 79-112

    6. The Cerebellar GABAAR System as a Potential Target for Treating Alcohol Use Disorder

      • David J. Rossi, Ben D. Richardson
      Pages 113-156

    7. Do Alcohol-Related AMPA-Type Glutamate Receptor Adaptations Promote Intake?

      • F. Woodward Hopf, Regina A. Mangieri
      Pages 157-186

    8. Molecular, Neuronal, and Behavioral Effects of Ethanol and Nicotine Interactions

      • Paul M. Klenowski, Andrew R. Tapper
      Pages 187-212

    9. Cross-Species Alterations in Synaptic Dopamine Regulation After Chronic Alcohol Exposure

      • Cody A. Siciliano, Anushree N. Karkhanis, Katherine M. Holleran, James R. Melchior, Sara R. Jones
      Pages 213-238

    10. Central Noradrenergic Interactions with Alcohol and Regulation of Alcohol-Related Behaviors

      • Elena M. Vazey, Carolina R. den Hartog, David E. Moorman
      Pages 239-260

  3. Ion Channels

    1. Front Matter

      Pages 261-261
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    2. Voltage-Sensitive Calcium Channels in the Brain: Relevance to Alcohol Intoxication and Withdrawal

      • Prosper N’Gouemo
      Pages 263-280

    3. Voltage-Sensitive Potassium Channels of the BK Type and Their Coding Genes Are Alcohol Targets in Neurons

      • Alex M. Dopico, Anna N. Bukiya, Jill C. Bettinger
      Pages 281-309

    4. Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior

      • Reginald Cannady, Jennifer A. Rinker, Sudarat Nimitvilai, John J. Woodward, Patrick J. Mulholland
      Pages 311-343

  4. Neuroimmune System

    1. Front Matter

      Pages 345-345
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    2. Hepatic Immune System: Adaptations to Alcohol

      • Adam Kim, Rebecca L. McCullough, Kyle L. Poulsen, Carlos Sanz-Garcia, Megan Sheehan, Abram B. Stavitsky et al.
      Pages 347-367

    3. Innate Immune Signaling and Alcohol Use Disorders

      • Leon G. Coleman Jr., Fulton T. Crews
      Pages 369-396

    4. Ethanol and Cytokines in the Central Nervous System

      • Marisa Roberto, Reesha R. Patel, Michal Bajo
      Pages 397-431

  5. Neuropeptides and Genomics

    1. Front Matter

      Pages 433-433
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Keywords

About this book

This volume gives an overview of new insights to alcohol pharmacology using DREADDs (Designer Receptors and Unraveling the Neuropharmacology of Alcohol). It examines which pharmacological principles should be applied to understanding DREADDs taking into account some very current research. Additionally, this book covers important topics under the heading of “experimental pharmacology” and alcohol.

Editors and Affiliations

  • Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, USA

    Kathleen A. Grant

  • Laboratory for Integrative Neuroscience, National Institutes of Health, Bethesda, USA

    David M. Lovinger

Bibliographic Information

  • Book Title: The Neuropharmacology of Alcohol

  • Editors: Kathleen A. Grant, David M. Lovinger

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-319-96523-9

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2018

  • Hardcover ISBN: 978-3-319-96522-2Published: 08 April 2019

  • eBook ISBN: 978-3-319-96523-9Published: 27 March 2019

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XI, 625

  • Number of Illustrations: 4 b/w illustrations, 32 illustrations in colour

  • Topics: Pharmacology/Toxicology, Neurosciences, Psychopharmacology

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