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Hydroxy-Pyridones as Antifungal Agents with Special Emphasis on Onychomycosis

  • Conference proceedings
  • © 1999

Overview

Editors:
  1. Sam Shuster

    1. Department of Dermatology Framlington Place, University of Newcastle upon Tyne, Newcastle upon Tyne, England

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Table of contents (17 papers)

  1. Front Matter

    Pages I-X
    Download chapter PDF

  2. Hydroxy-Pyridones Outstanding Biological Properties

    • A. Markus
    Pages 1-10

  3. Enzyme Histochemical Investigations of Candida albicans After Treatment with Rilopirox, a Novel Fungicidal Hydroxy-Pyridone

    • H. K. Reitze, K.-A. Seitz, D. R. Dannhorn, H. Hänel, M. Bohn
    Pages 11-17

  4. Can Ciclopirox Be Used as a Broad-Spectrum Anti-Infective Agent?

    • W. Schalla, K. Kraemer, R. Pooth
    Pages 18-32

  5. Studies of the Anti-Inflammatory Properties of Ciclopirox

    • J. L. Rees
    Pages 33-35

  6. Measurement of Ciclopirox Permeation Through Fingernail Models by Novel Spectroscopic Techniques

    • T. M. Bayerl
    Pages 36-38

  7. Dermatomycosis: A Multifactorial Disease

    • M. A. J. Allevato
    Pages 39-42

  8. Efficacy of Topical Batrafen

    • S. A. Burova
    Pages 43-44

  9. Ciclopirox Gel Treatment of Scalp Seborrheic Dermatitis

    • B. B. Abrams, R. J. Cherill, R. Ramaswamy, H. I. Katz
    Pages 45-50

  10. Seborrhoeic Dermatitis and Dandruff, and Its Treatment With Ciclopirox Shampoo

    • S. Shuster
    Pages 51-55

  11. Epidemiology of Mycological Infections in Children—in South America

    • F. M. Gonzalez Otero
    Pages 56-61

  12. Clinical Efficacy of Topical Ciclopirox Nail Lacquer: Double-Blind United States Studies on Onychomycosis

    • R. Scher
    Pages 62-68

  13. Dose Regimen Studies with Ciclopirox Nail Lacquer

    • G. Wozel
    Pages 69-74

  14. Open Studies of Ciclopirox Nail Lacquer in Onychomycosis—A Review

    • S. Nolting
    Pages 75-80

  15. Influence of Onychomycosis on the Quality of Life

    • A. Stary, S. Torma, P. G. Sator
    Pages 81-90

  16. Treatment of Onychomycoses: Pharmacoeconomic Aspects

    • T. R. Einarson, P. I. Oh, N. Shear
    Pages 91-95

  17. The Safety Aspects of Systemic and Topical Antifungal Agents Used in the Management of Onychomycosis

    • A. K. Gupta
    Pages 96-102

  18. Differential Diagnosis of Onychomycosis and Rationale for a Step-Therapy in Treating Nail Fungal Infection

    • R. Baran
    Pages 103-109
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Keywords

About this book

This book summarizes the results of two symposia held on hydroxy-pyridones as antifungal agents organized on the occasion of the International Summit on Cutaneous Antifungal Therapy 1996 in Vancouver and the 19th World Congress of Dermatology 1997 in Sydney. Some of the papers deal with the basic mechanisms of action and how these translate into product features, e.g. activity spectrum. Other papers describe the unique properties of hydroxy-pyridones, such as high penetration into and through keratinic tissues or their activity as dual inhibitor on 5-lipoxygenase and cyclooxygenase which leads to a remarkable antiinflammatory effect. Last but not least various accounts are given which show how this unique product profile aids the treatment of various fungal diseases, especially onychomycosis.

Editors and Affiliations

  • Department of Dermatology Framlington Place, University of Newcastle upon Tyne, Newcastle upon Tyne, England

    Sam Shuster

Bibliographic Information

  • Book Title: Hydroxy-Pyridones as Antifungal Agents with Special Emphasis on Onychomycosis

  • Editors: Sam Shuster

  • DOI: https://doi.org/10.1007/978-3-642-58401-5

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1999

  • Softcover ISBN: 978-3-540-65494-0Published: 08 March 1999

  • eBook ISBN: 978-3-642-58401-5Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: X, 109

  • Number of Illustrations: 72 b/w illustrations

  • Topics: Pharmacology/Toxicology, Medical Microbiology, Dermatology

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