Pharmacotherapeutics of the Thyroid Gland

1. Front Matter

   Pages I-XVIII

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2. Introduction: Clinical Aspects of Thyroid Treatment

   • A. D. Toft

   Pages 1-10

3. Control of TRH and TSH Secretion

   • M. F. Scanlon

   Pages 11-31

4. The TSH Receptor

   • M. Misrahi, E. Milgrom

   Pages 33-73

5. Thyroid Hormone Synthesis, Plasma Membrane Transport and Metabolism

   • G. Hennemann, T. J. Visser

   Pages 75-117

6. Thyroid Hormone Transport

   • J. R. Stockigt, C.-F. Lim, J. W. Barlow, D. J. Topliss

   Pages 119-150

7. Molecular Biology of Thyroid Hormone Action

   • J. A. Franklyn, V. K. K. Chatterjee

   Pages 151-170

8. Iodine: Metabolism and Pharmacology

   • S. Nagataki, N. Yokoyama

   Pages 171-188

9. Antithyroid Drugs: Their Mechanism of Action and Clinical Use

   • M. El Sheikh, A. M. McGregor

   Pages 189-206

10. Effect of Lithium on the Thyroid Gland

    • J. H. Lazarus

    Pages 207-223

11. Amiodarone and the Thyroid

    • W. M. Wiersinga

    Pages 225-287

12. Effects of Other Pharmacological Agents on Thyroid Function

    • C. A. Meier, A. G. Burger

    Pages 289-300

13. Effects of Environmental Agents on Thyroid Function

    • E. Gaitan

    Pages 301-317

14. Thyroid Hormone Antagonism

    • J. W. Barlow, T. C. Crowe, D. J. Topliss

    Pages 319-342

15. Immunomodulatory Agents in Autoimmune Thyroid Disease

    • A. P. Weetman

    Pages 343-360

16. Back Matter

    Pages 361-370

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All the important pharmacological interactions affecting thyroid function are described in this book. The first section is devoted to the physiology and biochemistry of thyroid disease, putting the pharmacological interactions into perspective. The second section reviews all the important pharmacological effects on thyroid function and also deals with the impact of other environmental agents. The chapters are written by internationally recognised experts and extensively referenced to provide an up-to-date review of the pharmacological interactions important to the thyroid and its diseases.

• Schilddrüsenerkrankung
• biochemistry
• biology
• chemistry
• cytokine
• drug
• hormone
• kinetics
• metabolism
• neurotransmitter
• nuclear receptors
• pharmacokinetics
• pharmacology
• physiology
• thyroid hormone

• Department of Medicine Clinical Sciences Centre Northern General Hospital, The University of Sheffield, Sheffield, UK

  A. P. Weetman

• Department of Endocrinology, St. Bartholomew’s Hospital, London, UK

  A. Grossman

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