Implications of Psychopharmacology to Psychiatry

1. Front Matter

   Pages i-x

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2. Neurotransmitter Interactions Important for Schizophrenia

   • A. Carlsson

   Pages 1-12

3. The Etiology of Affective Illness

   • F. K. Goodwin

   Pages 13-22

4. New Findings in the Genetics of Bipolar Illness

   • E. S. Gershon

   Pages 23-33

5. Targeting the Action of Antidepressant Drugs on Second-Messenger Systems

   • G. Racagni, M. Popoli, S. Mori, N. Brunello, J. Perez

   Pages 34-40

6. New Concepts of Schizophrenia Derived from Epidemiological Research

   • H. Häfner

   Pages 41-55

7. The Course of Psychiatric Disorders as a Diagnostic Tool

   • J. Angst

   Pages 56-65

8. A Psychoanalytic Model for the Classification of Personality Disorders

   • O. F. Kernberg

   Pages 66-78

9. Functional Psychopathology: An Essential Diagnostic Step in Biological Psychiatric Research

   • H. M. van Praag

   Pages 79-88

10. The Development of Nosological Concepts in Anxiety Disorders

    • D. F. Klein

    Pages 89-100

11. Classification of the Affective and Related Disorders

    • Martin Roth, Dorgival Caetano

    Pages 101-126

12. The Ideal Neuroleptic

    • M. Lader

    Pages 127-137

13. Long-Term Treatment of Schizophrenia

    • J. M. Kane

    Pages 138-149

14. Treatment of Affective Disorders

    • S. A. Montgomery

    Pages 150-157

15. Negative Symptoms of Schizophrenia: Methodological Issues, Biochemical Findings and Efficacy of Neuroleptic Treatment

    • H.-J. Möller, M. L. Rao

    Pages 158-178

16. Interaction of Long-Term Antidepressant Treatment with Psychosocial Factors

    • F. Bauwens, D. Pardoen, J. Mendlewicz

    Pages 179-187

17. Back Matter

    Pages 189-189

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The discovery of chlorpromazine for the specific treatment of schizophrenic symp­ toms and, later on, of imipramine for the specific treatment of depressive symptoms marked a new milestone in clinical psychiatry and basic neuroscience 40 years ago. The exploration of biochemical mechanisms of action of these psychotropic drugs created new theories on the pathophysiology of psychiatric disorders, such as the dopamine hypothesis of schizophrenia and the catecholamine and serotonin hypotheses of depression. Thus the discovery of these biological treatments had a major impact on natural science-oriented research. Biological psychiatry as we know it today has its origin in these psychopharmacological drugs and influences many disciplines in psychiatry. It was a fortunate coincidence that Hans Hippius, whose 70th birthday we celebrated this year with an international symposium, started his professional career during this time in the 1950S. He was one of the early pioneers in clinical psycho­ pharmacological research and enthusiastic about both the scientific and the thera­ peutic prospects of the new psychotropic drugs. He has worked in this field for more than three decades and has made many lasting contributions to biological psychiatry. Among the many activities, his contributions in the development of the new atypical antipsychotic drug clozapine should be mentioned.

• Behandlung psychischer Störungen
• Feldtheorie
• Psychiatrie
• Psychopharmaology
• Psychopharnakologie
• Treatment of mental disorders
• drug
• drug development
• elektromagnetische Felder und Wellen
• field theory
• pharmacology
• psychiatric disorder
• psychiatry
• psychopharmacology
• research

• Psychiatrische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, München, Deutschland

  M. Ackenheil, B. Bondy, R. Engel, M. Ermann, N. Nedopil

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