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Non-coding RNA and the Reproductive System

  • Book
  • © 2016

Overview

Editors:
  1. Dagmar Wilhelm

    1. Department of Anatomy and Neuroscience, The University of Melbourne Department of Anatomy and Neuroscience, Parkville, Australia

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  2. Pascal Bernard

    1. School of BioSciences, The University of Melbourne School of BioSciences, Melbourne, Australia

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    You can also search for this editor in PubMed   Google Scholar

  • Presents a unique collection of the latest advances in identifying and understanding the role of non-coding RNA in sexual differentiation
  • Covers both the role of non-coding RNAs in the development of the reproductive system and their implication in disease, such as breast and prostate cancer
  • Comprehensive coverage of the function of non-coding RNAs in the development and disease of the reproductive system forms an invaluable basis for further functional studies
  • Written by international experts in their field who provide the very latest details on non-coding RNA function

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 886)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-vii
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  2. The Reproductive System

    • Andrew Pask
    Pages 1-12

  3. Non-coding RNAs: An Introduction

    • Jennifer X. Yang, Raphael H. Rastetter, Dagmar Wilhelm
    Pages 13-32

  4. How Many Non-coding RNAs Does It Take to Compensate Male/Female Genetic Imbalance?

    • Jean-François Ouimette, Claire Rougeulle
    Pages 33-49

  5. The piRNA Pathway Guards the Germline Genome Against Transposable Elements

    • Katalin Fejes Tóth, Dubravka Pezic, Evelyn Stuwe, Alexandre Webster
    Pages 51-77

  6. Non-coding RNA in Ovarian Development and Disease

    • J. Browning Fitzgerald, Jitu George, Lane K. Christenson
    Pages 79-93

  7. Non-coding RNA in Spermatogenesis and Epididymal Maturation

    • J. E. Holt, S. J. Stanger, B. Nixon, E. A. McLaughlin
    Pages 95-120

  8. Non-coding RNAs in Mammary Gland Development and Disease

    • Gurveen K. Sandhu, Michael J. G. Milevskiy, Wesley Wilson, Annette M. Shewan, Melissa A. Brown
    Pages 121-153

  9. Non-coding RNAs in Prostate Cancer: From Discovery to Clinical Applications

    • Yvonne Ceder
    Pages 155-170

  10. Non-coding RNAs in Uterine Development, Function and Disease

    • Warren B. Nothnick
    Pages 171-189

  11. Back Matter

    Pages 191-198
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Keywords

About this book

This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract.

The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.

Editors and Affiliations

  • Department of Anatomy and Neuroscience, The University of Melbourne Department of Anatomy and Neuroscience, Parkville, Australia

    Dagmar Wilhelm

  • School of BioSciences, The University of Melbourne School of BioSciences, Melbourne, Australia

    Pascal Bernard

Bibliographic Information

  • Book Title: Non-coding RNA and the Reproductive System

  • Editors: Dagmar Wilhelm, Pascal Bernard

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-94-017-7417-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B.V. 2016

  • Hardcover ISBN: 978-94-017-7415-4Published: 18 December 2015

  • Softcover ISBN: 978-94-024-1344-1Published: 30 March 2019

  • eBook ISBN: 978-94-017-7417-8Published: 11 December 2015

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: VII, 198

  • Number of Illustrations: 26 b/w illustrations

  • Topics: Gene Function, Developmental Biology, Reproductive Medicine

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