The Plasticity of Skeletal Muscle

From Molecular Mechanism to Clinical Applications

Editors: Sakuma, Kunihiro (Ed.)

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  • Discusses plasticity of skeletal muscle from the perspectives of the biochemical, biophysical, pathological, metabolic and nutritional implications
  • Describes the molecular mechanism of the various adaptations of skeletal muscle and practical applications in various muscular disorders such as muscular dystrophy and sarcopenia
  • A valuable professional reference source for physicians and researchers in the field of sports science
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eBook $149.00
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  • ISBN 978-981-10-3292-9
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Hardcover $199.99
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Softcover $199.99
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About this book

This book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis.

The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It also explains the roles of biological mediators such as PGC-1, transient receptor potential cation channels (TRPC), and AMPK in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome biogenesis, and redox regulation of mechanotransduction to modulate skeletal muscle mass are also covered.

It is an essential resource for physicians, researchers, post-docs as well as graduate students in the field of sports science including rehabilitation therapy, exercise physiology, exercise biochemistry, and molecular biology dealing with skeletal muscle.

About the authors

Professor Kunihiro Sakuma, Ph.D., currently works at Department for Liberal Arts in Tokyo Institute of Technology. He is a Physiologist working in the field of skeletal muscle. He was awarded sports science diploma in 1995 by the University of Tsukuba and started scientific work at the Department of Physiology, Aichi Human Science Center, focusing on the molecular mechanism of congenital muscular dystrophy and normal muscle regeneration. His interest later was turned to the molecular mechanism and the attenuating strategy of sarcopenia (age-related muscle atrophy). Preventing sarcopenia is important for maintaining a high quality of life in the aged population. His opinion is to attenuate sarcopenia by improving atutophagic defect using nutrient- and pharmaceutical-based treatments.

Table of contents (13 chapters)

Table of contents (13 chapters)

Buy this book

eBook $149.00
price for USA
  • ISBN 978-981-10-3292-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover $199.99
price for USA
Softcover $199.99
price for USA

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Bibliographic Information

Bibliographic Information
Book Title
The Plasticity of Skeletal Muscle
Book Subtitle
From Molecular Mechanism to Clinical Applications
Editors
  • Kunihiro Sakuma
Copyright
2017
Publisher
Springer Singapore
Copyright Holder
Springer Nature Singapore Pte Ltd.
eBook ISBN
978-981-10-3292-9
DOI
10.1007/978-981-10-3292-9
Hardcover ISBN
978-981-10-3291-2
Softcover ISBN
978-981-10-9835-2
Edition Number
1
Number of Pages
IX, 292
Number of Illustrations
7 b/w illustrations, 14 illustrations in colour
Topics