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Autophagy: Biology and Diseases

Clinical Science

  • Book
  • © 2020

Overview

Editors:
  1. Weidong Le

    1. Liaoning Provincial Center for Clinical Research on Neurological Diseases, The First Affiliated Hospital, Dalian Medical University, Dalian, China

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  • Systematically summarizing the cutting-edge knowledge in the study of autophagy
  • Thoroughly discussing on the functions of autophagy in various diseases in major systems
  • Serving as a critical reference tool for researchers and clinicians

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1207)

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Table of contents (55 chapters)

  1. Front Matter

    Pages i-xxxvi
    Download chapter PDF

  2. Autophagy and Neuropsychological Disorders

    1. Front Matter

      Pages 1-1
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    2. Autophagy and Alzheimer’s Disease

      • Sheng Chen, Qinming Zhou, You Ni, Weidong Le
      Pages 3-19

    3. Autophagy and Parkinson’s Disease

      • Jiahong Lu, Mingyue Wu, Zhenyu Yue
      Pages 21-51

    4. Autophagy and Motor Neuron Diseases

      • Xiaojie Zhang, Kang Yang, Weidong Le
      Pages 53-74

    5. Autophagy and Prion Disease

      • Zongbing Hao, Guanghui Wang
      Pages 75-85

    6. Autophagy and Lysosome Storage Disorders

      • Haigang Ren, Guanghui Wang
      Pages 87-102

    7. Autophagy and Mitochondrial Encephalomyopathies

      • Xiangnan Zhang, Yanrong Zheng, Zhong Chen
      Pages 103-110

    8. Autophagy and Ischemic Stroke

      • Yanlin Zhang, Yongjun Cao, Chunfeng Liu
      Pages 111-134

    9. Autophagy and Hemorrhagic Stroke

      • Yanlin Zhang, Chunfeng Liu
      Pages 135-147

    10. Autophagy and Polyglutamine Disease

      • Haigang Ren, Zongbing Hao, Guanghui Wang
      Pages 149-161

    11. Autophagy and Epilepsy

      • Meihong Lv, Quanhong Ma
      Pages 163-169

    12. Autophagy in Neurodevelopmental Disorders

      • Meihong Lv, Quanhong Ma
      Pages 171-182

    13. Autophagy and Pituitary Adenoma

      • Zhebao Wu, Weiting Gu
      Pages 183-194

    14. Autophagy and Schizophrenia

      • Yuexiong Yang, Lin Xu
      Pages 195-209

  3. Autophagy and Cardiovascular Diseases

    1. Front Matter

      Pages 211-211
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    2. Autophagy and Hypertension

      • Jie Du, Congcong Zhang, Wei Zhao
      Pages 213-216

    3. Autophagy and Myocardial Ischemia

      • Jie Du, Yulin Li, Wei Zhao
      Pages 217-222

    4. Autophagy and Heart Failure

      • Jie Du, Yan Liu, Jintao Fu
      Pages 223-227

    5. Autophagy, Myocarditis, and Cardiomyopathy

      • Jie Du, Yan Liu, Jintao Fu
      Pages 229-235
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Keywords

About this book

This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine

Editors and Affiliations

  • Liaoning Provincial Center for Clinical Research on Neurological Diseases, The First Affiliated Hospital, Dalian Medical University, Dalian, China

    Weidong Le

About the editor

Professor Weidong Le is a leading neurologist/neuroscientist with a focus on neurodegenerative diseases. He was a Professor of Neurology and Director of the Parkinson’s Disease Research Center at Baylor College of Medicine, USA, and also served as a joint Professor and Director of the Institute of Neurology at Shanghai Jiao-tong University School of Medicine and Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. Since 2013, he has been the Vice President of the First Affiliated Hospital of Dalian Medical University and Director of Liaoning Provincial Center for Clinical Research on Neurological Diseases. He has published over 250 papers in Science, JAMA, Nature Genetics, Autophagy, Brain and Alzheimer’s & Dementia and other international journals. He has been awarded 28 research grants, including 3 NIH R0-1 projects. He is a member of the review committee of NIH, VA, INSERM, Singapore Academy of Science, and the Chinese Nature Science Foundation. He is also the Section Editor of the Brain Research Bulletin, Associate Editor of the Neuroscience Bulletin, Journal of Alzheimer’s Disease, and Cancer Medicine, and editorial board member of Autophagy, Alzheimer’s Dementia, Translational Neurodegeneration and the Journal of Neurochemistry. Professor Le has been named by Elsevier publishing house as one of the “Most Cited Chinese Researchers” for 5 consecutive years, from 2014-2018.

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