Overview
- Editors:
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Yury Verlinsky
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Reproductive Genetics Institute, Chicago, USA
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Anver Kuliev
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Reproductive Genetics Institute, Chicago, USA
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Table of contents (34 chapters)
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Clinical Aspects of Preimplantation Genetics
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Front Matter
Pages 153-153
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- Andre Van Steirteghem, Jiaen Liu, Etienne Van den Abbeel, Inge Liebaers, Paul Devroey
Pages 155-164
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- Bruno Brambati, Leonardo Formigli
Pages 165-174
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Gene Expression in Preimplantation Development and Gene Therapy
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Front Matter
Pages 187-187
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- Claudia Kappen, Frank H. Ruddle
Pages 189-201
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Ethical and Legal Aspects of Preimplantation Genetics
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Front Matter
Pages 231-231
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- Anver Kuliev, Bernadette Modell
Pages 233-244
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Technical Aspects of Preimplantation Genetics
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Front Matter
Pages 271-271
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- Yury Verlinsky, Jeanine Cieslak, Sergei Evsikov
Pages 273-278
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- Henry E. Malter, Beth E. Talansky, Jacques Cohen
Pages 279-284
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- Renee Martin, Evelyn Ko, Leona Barclay
Pages 285-292
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- Alan H. Handyside, Eleni H. Kontogianni
Pages 299-304
About this book
Yury Verlinskyand Anver Kuliev Reproductive Genetics Institute, Illinois Masonic Medical Center, 836 W. Wellington chicago, IL 60657 Although introduction of a first trimester prenatal diagnosis by chorionic viIIus sampling (CVS) has considerably improved the possibility for prevention of genetic diseases, it requires a selective abortion in case of an affected fetus. Following the direction of an earlier prenatal diagnosis and to avoid the need for abortion, preimplantation genetic diagnosis has been initiated based on polar body removal and pre-embryo biopsy. The First International symposium on Preimplantation Genetics, Chicago, September 17-19, 1990, was organized to explore these important developments, to review the state of knowledge in the field, and to address existing problems to be solved for developing and improving current approaches for preimplantation diagnosis of genetic disorders. A growing interest in the subject was obvious from the wide attendance of the meeting: over 250 scientists from 19 countries participated. This was the first attempt to put together the advances in different areas of basic and applied research relevant to Preimplantation Genetic Diagnosis, with the multidisciplinary scientific program including the sessions on embryology, micromanipulation and biopsy, genetic analysis of gametes and pre-embryos, IVF, gene expression and gene therapy, and ethical and legal issues. The deliberations of the Symposium presented in the above mentioned sessions, which comprise the contents of correspond ing sections of the Proceedings, open a newarea in medical research based on the interaction of IVF and New Genetics.